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Clinical Application of delayed Gadolinum Enhanded MRI of Cartilage (dGEMRIC) Marcel Dudda, M.D.; Young Jo Kim, M.D., Ph.D. | 2009-07-13 MAGNETOM Marketing Tool Kit

Delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC) is used to assess cartilage glycosaminoglycan distribution. Our aim was to determine the relationships between self-reported pain and disability, clinical variables, and serum leptin, and dGEMRIC indices in obese subjects with and without clinical knee osteoarthritis (OA). magnetic resonance imaging of cartilage (dGEMRIC index, ms). Images were taken using a Siemens Magnetom Symphony Quan-tum 1.5-T scanner (Siemens AG, Medical Solutions, Erlangen, Ger-many). Single sagittal slice images from the centre of the medial and lateral femoral condyles were taken from the knee with the highest K/L grade (affected knee).

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MRISubjects were investigated with dGEMRIC 20.6 years (mean; range 18e23) after the injury, using a standard 1.5 T MRI system with a dedicated knee coil (Magnetom Vision; Siemens Medical Solutions, Erlangen, Germany). MRI with dGEMRIC was more sensitive than morphological MRI, and lower dGEMRIC values were found for clock positions with impingement as detected on 3D-CT. This could aid in patient-specific diagnosis of FAI, preoperative patient selection, and surgical decision making to identify patients with cartilage damage who are at risk for inferior outcomes after hip arthroscopy. Methods: Twenty-seven participants (age = 28.8 ± 8.6 yrs; BMI = 24.2 ± 2.3 kg m −2; 44% females) diagnosed with FAI syndrome (cam-, pincer- or combined-type FAI morphology concurrent with symptoms) underwent hip MRI with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in one of two 3T scanners (Siemens Prisma, Siemens Skyra). The dGEMRIC imaging was performed 60 min after the injection. The Variable flip angle method with two 3D gradient echo sequences was used for acquisition of images for T1 calculation (MapIt, Siemens Healthcare, Erlangen, Germany). The two sequences had flip angles 5 and 30 respectively.

software (Siemens). The dGEMRIC index was analyzed on seven di erent articular facets: the medial and lateral femoral condyle, femoral trochlea, medial and lateral tibial condyle and both patellar facets, before the intra-articular application of stem cells and in any subsequent MRI examination at three, nine,

dGEMRIC delayed gadolinium-enhanced MRI of cartilage All data were acquired on a 1.5 Tesla Siemens Sonata whole-body scanner  USING AUTOMATIC EXPOSURE CONTROL IN CT – SIEMENS CARE DOSE disease in young adulthood: a 21-year follow-up study including dGEMRIC. Introduction: dGEMRIC (delayed Gadolinium Enhanced Magnetic (MR5) and Siemens Prisma 3 T (MR6), using a standard head receive coil.

Dgemric siemens

Objective: To prospectively compare chemical-exchange saturation-transfer (CEST) with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and T2 mapping to assess the biochemical cartilage properties of the knee. Method: Sixty-nine subjects were prospectively included (median age, 42 years; male/female = 32/37) in three cohorts: 10 healthy volunteers, 40 patients with clinically suspected

Dgemric siemens

The patients were examined using a standard knee MRI protocol [13] that was developed and used at Oslo University Hospital and included T2 mapping and a dGEMRIC [14]. The patients were scanned with all of the different sequences 2018-04-01 · All patients were investigated in a standard 1.5 T MRI system (MAGNETOM Avanto, Siemens AG, Erlangen, Germany) with two flexible Body Matrix coils positioned directly over the hips. Patients received 0.2 mg/kg Gd(DTPA) 2− (Magnevist ® , Schering AG, Berlin, Germany) intravenously, followed by a 10 min timed walk. dGEMRIC imaging was performed 60 min after the injection. The Siemens South Africa head office in Johannesburg has implemented a Distributed Energy System (DES) as a solution to tackle Africa’s energy transition. Th This definition approximates grade 2 knee OA based on the Kellgren and Lawrence scale 36 .

EVALUATION METHODSThe evaluation included dGEMRIC, isokinetic tests of muscle strength, a functional performance test and calculation of BMI. dGEMRIC A 1.5 T MRI system (Magnetom Vision; Siemens Medical Systems, Erlangen, Germany) with a dedicated knee coil was used for the examinations as previously described 12,20 . 2018-04-01 The dGEMRIC Index was 14.4% lower in the medial index compartment (374 61 ms, mean SD) than in the lateral reference compartment (437 59 ms, mean SD) (P<0.001). The dGEMRIC Index of the medial diseased compartment correlated positively with both knee flexor (r¼0.50, P¼0.001) and knee extensor Using delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) (Magnetom Skyra, Siemens) and a dedicated 16-channel hand coil. 2020-01-01 using 3D dGEMRIC at two different doses of the contrast agent Gd-DTPA2-. Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight). The relaxation time (T 1) and relaxation rate (R 1 =1/T sequences using a 3T MRI scanner (Magnetom Skyra, Siemens) and a dedicated 16-channel hand coil. Images were analyzed by two independent raters for dGEMRIC indices, PsA MRI scores (PsAMRIS), and All MR imaging was performed on a 3T MR scanner (MAGNETOM Skyra, Siemens Healthcare, Erlangen, Germany) with a 15-channel Tx/Rx knee coil.
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Dgemric siemens

Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is an imaging method for detecting early damage to cartilage. Furthermore, we defined dGEMRIC and T map- (Siemens Healthcare), which provides the protocols and inline cal- ping reference values for healthy and diseased cartilage of culation of parametric maps of T and T properties of the imaged 1 2 the wrist at 3T. tissue and automatically generates parametric color-coded maps. MR IMAGINGThe MR images were performed on a 1.5T magnet (Symphony; Siemens, Erlangen, Germany) using a quadrature knee coil (Siemens, Erlangen, Germany).

EVALUATION METHODSThe evaluation included dGEMRIC, isokinetic tests of muscle strength, a functional performance test and calculation of BMI. dGEMRIC A 1.5 T MRI system (Magnetom Vision; Siemens Medical Systems, Erlangen, Germany) with a dedicated knee coil was used for the examinations as previously described 12,20 . Using dGEMRIC, several studies have shown a strong correlation of local joint in-flammation and early cartilage alterations in RA [24,25].
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MRISubjects were investigated with dGEMRIC 20.6 years (mean; range 18e23) after the injury, using a standard 1.5 T MRI system with a dedicated knee coil (Magnetom Vision; Siemens Medical Solutions, Erlangen, Germany). MRI with dGEMRIC was more sensitive than morphological MRI, and lower dGEMRIC values were found for clock positions with impingement as detected on 3D-CT. This could aid in patient-specific diagnosis of FAI, preoperative patient selection, and surgical decision making to identify patients with cartilage damage who are at risk for inferior outcomes after hip arthroscopy. Methods: Twenty-seven participants (age = 28.8 ± 8.6 yrs; BMI = 24.2 ± 2.3 kg m −2; 44% females) diagnosed with FAI syndrome (cam-, pincer- or combined-type FAI morphology concurrent with symptoms) underwent hip MRI with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in one of two 3T scanners (Siemens Prisma, Siemens Skyra).


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The majority of dGEMRIC studies have been in the knee and hip, although there are a number of reports of dGEMRIC applied to the finger joints [12, 50–52] and ankle . dGEMRIC protocols have also been applied in the meniscus [54–56] and intervertebral discs [57, 58]; however, the considerations of transport are much more of a concern in these thick tissues, and the interpretation of the

The dGEMRIC imaging was performed 60 min after the injection. The Variable flip angle method with two 3D gradient echo sequences was used for acquisition of images for T1 calculation (MapIt, Siemens Healthcare, Erlangen, Germany). The two sequences had flip angles 5 and 30 respectively. Other scan parameters were: 3Tesla and specific sequences dgemric Siemens a positive structural effect on the proteoglycan content of the articular cartilage of the knee.

Delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) in Hip Dysplasia Marcel Dudda, M.D.; et al. Dept. of Orthopaedic Surgery, Children’s Hospital Boston, Harvard Medical School, Boston, USA

Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight). The relaxation time (T 1) and relaxation rate (R 1 =1/T sequences using a 3T MRI scanner (Magnetom Skyra, Siemens) and a dedicated 16-channel hand coil. Images were analyzed by two independent raters for dGEMRIC indices, PsA MRI scores (PsAMRIS), and All MR imaging was performed on a 3T MR scanner (MAGNETOM Skyra, Siemens Healthcare, Erlangen, Germany) with a 15-channel Tx/Rx knee coil.

Images were analyzed by two independent raters for dGEMRIC indices, PsA MRI scores (PsAMRIS) and total  Apr 17, 2019 the manual 3-D analysis of regional patterns of dGEMRIC index 3T scanner ( Trio; Siemens, Erlangen, Germany) [44] using a. 6-channel  av C Siversson — BMI body mass index. dGEMRIC delayed gadolinium-enhanced MRI of cartilage All data were acquired on a 1.5 Tesla Siemens Sonata whole-body scanner  USING AUTOMATIC EXPOSURE CONTROL IN CT – SIEMENS CARE DOSE disease in young adulthood: a 21-year follow-up study including dGEMRIC.